Medical Management of Cronkhite-Canada Syndrome

Eric Ward, MD, Herbert C. Wolfsen, MD, Christine Ng, MD


South Med J. 2002;95(2) 

In This Article

Sidebar: Keypoints

  • The Cronkhite-Canada syndrome is a rare, noninherited nonadenomatous gastrointestinal polyposis syndrome.

  • The etiology and pathogenesis of this syndrome are unknown.

  • Characteristic dermatologic abnormalities include hyperpigmentation, alopecia, and onychodystrophy.

  • No medical therapy has been demonstrated to be consistently effective to date.

  • This report describes sustained clinical and endoscopic responses in a patient with Cronkhite-Canada syndrome who was treated with a novel medical regimen.


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