Impact of Persistent Subclinical Hypothyroidism on Clinical Outcomes in Non-ST-Segment Elevation Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention

Chuyi Han; Kaihang Xu; Le Wang; Yingyi Zhang; Rui Zhang; Ao Wei; Lijie Dong; Yuecheng Hu; Jinghan Xu; Wenyu Li; Tingting Li; Chunwei Liu; Wei Qi; Dongxia Jin; Jingxia Zhang; Hongliang Cong


Clin Endocrinol. 2022;96(1):70-81. 

In This Article


The preoperative TSH levels and the changes in thyroid hormone levels during follow-up after PCI in NSTE-ACS patients are clinically crucial. It was noted in this study that an increase in TSH level was associated with a poor clinical outcome. For such patients, it is more important to monitor changes in thyroid function and recurrence of cardiovascular events. Our results suggest that persistent SCH is associated with increased severity of coronary artery lesions and MACCE, and may be a prognostic predictor in patients with NSTE-ACS treated with PCI.