Predictors of 30-Day Readmissions for Adrenal Insufficiency

A Retrospective National Database Study

Asim Kichloo; Zain El-amir; Hafeez Shaka; Farah Wani; Sofia Junaid Syed


Clin Endocrinol. 2021;95(2):269-276. 

In This Article


Adrenal insufficiency, a condition marked by deficiency in glucocorticoid production along the HPA axis, is a potentially deadly disease that can result in numerous hospital admissions. In a national readmission database, 17.3% of hospitalizations resulted in 30-day readmission, with the most common cause of readmission being AI. Readmissions were associated with increased mortality, longer mean LOS, higher THC and higher COH. Independent predictors of readmission were CCI of 3 or greater, being discharged against medical advice, protein-energy malnutrition and obesity. Based on the results of this study, we strongly believe that patients hospitalized with AI and the aforementioned predictors of readmission are at higher risk of readmission, which is associated with further complications, greater financial burden and death. Hence, aggressive yet appropriate monitoring should be considered for these hospitalized patients.