Global Timing of Hepatitis C Virus Elimination in High-income Countries

Homie Razavi; Yuri Sanchez Gonzalez; Cammy Yuen; Markus Cornberg


Liver International. 2020;40(3):522-529. 

In This Article


Of 45 high-income countries analyzed, nine (Australia, France, Iceland, Italy, Japan, South Korea, Spain, Switzerland and the United Kingdom) were on track towards eliminating HCV by 2030; three (Austria, Germany and Malta) by 2040; and three (Ireland, the Netherlands and Saudi Arabia) by 2050. The remaining 30 countries are not expected to eliminate HCV before 2050 (Table 1, Figure 2). Of the 45 analyzed countries, 19 (42%) had lifted restrictions on treatment based on fibrosis score by 2017. Excluding these treatment restrictions as a criterion for elimination, only three additional countries (Belgium, Canada and New Zealand) would be expected to eliminate HCV by 2050.

Figure 2.

Year of elimination of HCV by country. HCV, hepatitis C virus. Error bars reflect the best-case (lowest starting chronic prevalence) and worst-case (highest starting chronic prevalence) years of elimination

Of the four elimination targets, the reduction in incidence was the hardest to achieve, followed by the reduction in liver-related deaths due to HCV infections. By 2030, 34 countries are not expected to meet the incidence target, 30 countries are not expected to meet the mortality target, 26 countries are not expected to meet the treatment target and 21 countries are not expected to meet the diagnosis target.