First Look

• Microwave Ablation Alternative to Surgery for T2 Breast Tumors Investigators explored the use of microwave ablation to treat T2 breast tumors. The study was published as a preprint and has not yet been peer reviewed.
  First Look, March 22, 2023
• Causal Link Found Between T2D and Dementia A Mendelian randomization study in more than 300,000 mostly male US veterans found that those with type 2 diabetes were more likely to develop dementia, vascular dementia, and Alzheimer's disease.
  First Look, March 21, 2023
• Tissue-Sparing Resection, Ablation Option for NET Liver Mets Parenchymal-sparing liver resection with microwave ablation should be considered for NETs with many liver metastases. The study was published as a preprint and has not yet been peer reviewed.
  First Look, March 21, 2023
• Immune Checkpoint Inhibitors Pose ACTH Deficiency Risk Immune checkpoint inhibitors, increasingly used to treat a variety of cancers, can cause unpredictable immune-related adverse events including endocrinopathies.
  First Look, March 20, 2023
• Chemo Doesn't Improve Lung Adenocarcinoma Survival in Most Only never-smokers with high PDL-1 expression lived longer when chemotherapy was added to upfront PD-(L)1 blockers. The study was published as a preprint and has not yet been peer reviewed.
  First Look, March 09, 2023
• Does Walking Affect Fasting Glucose in Type 2 Diabetes? Among patients with type 2 diabetes living in low-income countries, a long walk to the clinic didn't change fasting glucose levels.
  First Look, March 08, 2023
• Safe to Skip Primary Tumor Boosts in Pediatric Germinomas A small review suggests no benefit from an extra dose of radiation even in children with residual disease. The study was published as a preprint and has not yet been peer reviewed.
  First Look, March 03, 2023
• Maternal Type 1 Diabetes Drives Congenital Heart Defects Review of more than 600,000 Finnish live births from 2006 to 2016 showed that mothers with type 1 diabetes had a nearly fourfold higher rate of children born with a congenital heart defect.
  First Look, February 28, 2023
• Skin Problems Common at Insulin Pump Infusion Sites Tissue changes from inflammatory responses could be responsible for infusion site failures.
  First Look, February 24, 2023
• Neoadjuvant Chemotherapy Underused in Breast Cancer If the initial consult is with a surgeon, women are more likely to have up-front surgery for breast cancer. The study was published as a preprint and has not yet been peer reviewed.
  First Look, February 23, 2023
• Heart Rate Variability Could Track With Risk for Type 2 Diabetes Lower autonomic nervous system function was associated with worse beta-cell function. Could modifying risk factors for neurodegeneration ultimately help prevent and/or slow the onset of type 2 diabetes?
  First Look, February 23, 2023
• Lenvatinib May Up Survival in Anaplastic Thyroid Cancer Among patients with unresectable anaplastic thyroid cancer treated with lenvatinib, average survival was prolonged. The study was published as a preprint and has not yet been peer reviewed.
  First Look, February 22, 2023
• Higher Insulin Resistance Predicts Incident T2D, CKD Prospectively collected data from 4314 South Korean adults showed that people with higher levels of insulin resistance have the greatest rate of incident type 2 diabetes and chronic kidney disease.
  First Look, February 22, 2023
• Strategy to Reduce Peritoneal Metastases in Gastric Cancer New data suggest hyperthermic intraperitoneal chemotherapy may help reduce peritoneal metastases after gastric cancer surgery. The study was published as a preprint and has not yet been peer reviewed.
  First Look, February 16, 2023
• Supported DIY Artificial Pancreas Systems Work for T1D Retrospective review of 248 adults and children with type 1 diabetes who received open-source artificial pancreas systems shows performance that rivals retail systems.
  First Look, February 15, 2023
• Key Factors Predict Gallbladder Cancer on Routine Cholecystectomy These predictive factors can allow for better surgical planning and treatment. The study was published as a preprint and has not yet been peer reviewed.
  First Look, February 10, 2023
• More Sleep Benefits People With Type 1 Diabetes Prospective data from 166 people with type 1 diabetes showed a significant association between longer sleep duration and improvements in next-day stress and mood.
  First Look, February 09, 2023
• 'Valid Option' for Partial Breast Irradiation in Breast Cancer A 1-week schedule of 30 Gy delivered in five daily fractions was safe and effective in patients with early breast cancer. The study was published as a preprint and has not been peer reviewed.
  First Look, February 07, 2023
• High Serum Klotho Protein Links With Less Osteoporosis High serum levels of klotho, a protein related to bone mineral density, might be a convenient and reliable way to identify postmenopausal women with a reduced risk for developing osteoporosis.
  First Look, February 06, 2023
• Cath Ablation for AF No Less Safe, Effective in Cancer Patients Freedom from recurrence or reablation and safety outcome were similar at 12 months regardless of whether patients had a recent cancer diagnosis or were on anthracyclines.
  First Look, February 03, 2023