First Look

• 'Valid Option' for Partial Breast Irradiation in Breast Cancer A 1-week schedule of 30 Gy delivered in five daily fractions was safe and effective in patients with early breast cancer. The study was published as a preprint and has not been peer reviewed.
  First Look, February 07, 2023
• High Serum Klotho Protein Links With Less Osteoporosis High serum levels of klotho, a protein related to bone mineral density, might be a convenient and reliable way to identify postmenopausal women with a reduced risk for developing osteoporosis.
  First Look, February 06, 2023
• Cath Ablation for AF No Less Safe, Effective in Cancer Patients Freedom from recurrence or reablation and safety outcome were similar at 12 months regardless of whether patients had a recent cancer diagnosis or were on anthracyclines.
  First Look, February 03, 2023
• Obesity Worsens Clinical Outcomes of Right Ventricular Dysfunction Among patients who had right heart catheterization, obesity was consistently associated with right ventricle dysfunction and increased risks of death and heart failure hospitalization within 7 years.
  First Look, February 02, 2023
• GLP-1 Agonists Protected Kidneys in T2D With Advanced DKD Among adults with type 2 diabetes and an eGFR < 30 mL/min/1.73m2, treatment with a GLP-1 agonist was associated with better renal preservation and survival compared with a DPP-4 inhibitor.
  First Look, January 31, 2023
• New Imaging Score May Predict Chemo Benefit in Early OPSCC If validated, this scoring system could help identify patients with oropharyngeal squamous cell carcinoma who can skip chemo. The study was published as a preprint and has not yet been peer reviewed.
  First Look, January 27, 2023
• Thyroid Hormone Reference Range May Not Apply for Cancer Patients Normal reference ranges of blood levels of thyroid-stimulating hormone and free thyroxine may not be suitable to determine thyroid function in patients with various types of cancer.
  First Look, January 25, 2023
• Who May Benefit Most From Liquid Biopsy Cancer Screening Tests? A new study explores the use of polygenic risk scores to assess the risk-benefit balance of early cancer detection testing. The study was published as a preprint and has not yet been peer reviewed.
  First Look, January 24, 2023
• Lung Cancer Risk Rises With A1c, Falls With Medication Prospective data from about 283,000 cancer-free people in a large database showed a significant positive link between incident lung cancer and A1c in people with diabetes or prediabetes.
  First Look, January 23, 2023
• Hypofractionated Radiation Can Increase Pain in Laryngeal SCC Investigators urge clinicians to be mindful of this issue. The study was published as a preprint and has not yet been peer reviewed.
  First Look, January 23, 2023
• LDL, Blood Pressure in T1D Differ From Background Levels A Dutch case-control study of 148,000 adults showed that among those with type 1 diabetes, average LDL-cholesterol and blood pressure levels diverged from those of the general background population.
  First Look, January 20, 2023
• Risk for New AF Climbs With Cardiometabolic Comorbidity Burden A larger burden of cardiometabolic disorders incurs a higher lifetime risk of atrial fibrillation, the effect more pronounced among women, suggests a cohort study.
  First Look, January 19, 2023
• Residual Beta-Cell Function May Protect Kidneys in Type 1 Diabetes Over half of participants still had insulin secretion beyond 3 years after diagnosis.
  First Look, January 18, 2023
• Stress Tolerance Influences Suicide Risk and Can Be Modified The study covered in this summary was published on ResearchSquare as a preprint and has not yet been peer reviewed.
  First Look, January 12, 2023
• Poor Oral Hygiene After Stroke Can Alter Inflammation Risk After severe and cardioembolic stroke, poor oral hygiene is associated with elevated blood inflammatory cytokine levels, researchers warning.
  First Look, January 12, 2023
• Low-Dose Chemo May Improve Survival in Advanced Cancer This study found a survival benefit with low-dose vs standard-dose chemotherapy for several common cancer types. The study was published as a preprint and has not yet been peer reviewed.
  First Look, January 12, 2023
• Rotavirus Vaccine Gives No Type 1 Diabetes Prevention Review of nearly 8000 Swedish children with incident type 1 diabetes showed no signal of a protective effect from rotavirus vaccination, which started in Sweden during 2014–2019.
  First Look, January 12, 2023
• Treat Subclinical Hypothyroidism in Pregnant Women: Study Pregnant women with subclinical hypothyroidism and no thyroid peroxidase antibodies who received levothyroxine had similar gestational diabetes and preeclampsia rates as others with normal thyroid.
  First Look, January 10, 2023
• Atezolizumab (Tecentriq) Tops Chemo for Platinum-ineligible NSCLC The checkpoint inhibitor was associated with better survival and adverse events vs single-agent chemo for advanced NSCLC. The study was published as a preprint and has not yet been peer reviewed.
  First Look, January 06, 2023
• Diabetes Link Found for Fuchs Corneal Endothelial Dystrophy In a case-control study of about 149,000 US military veterans, risk factors for Fuchs endothelial corneal dystrophy included diabetes, female sex, European ancestry, and other comorbidities.
  First Look, January 05, 2023