Internal Medicine News

• Continued Monkeypox Spread Can Lead to Viral Mutations Despite declining case numbers in the US and the UK, researchers emphasize that mitigation efforts are still necessary to prevent further spread of the virus.
  Medscape Medical News, September 27, 2022
• Coffee Linked to Reduced Cardiovascular Disease and Mortality Mild to moderate intake of ground, instant, and decaffeinated coffee is associated with lower mortality and cardiovascular disease risk, and can be considered part of a healthy diet, researchers say.
  Medscape Medical News, September 27, 2022
• ALS Drug Yields Meaningful Clinical Benefit, Phase 3 Data Show Longer-term data show the antisense oligonucleotide tofersen slows functional decline in patients with amyotrophic lateral sclerosis caused by superoxide dismutase 1 gene mutations.
  Medscape Medical News, September 27, 2022
• Flu Vaccine Not Linked to Increased Guillain-Barré Syndrome Risk Although past studies have suggested a link between the influenza vaccine and Guillain-Barré syndrome, a large new study showed no increased risk for older adults ― including those with comorbidities.
  Medscape Medical News, September 27, 2022
• What We Know About Long COVID So Far Long COVID: The name says it all. It's an illness that, for many people, has not yet stopped.
  Medscape Medical News, September 27, 2022
• Deep Brain Stimulation Effective for OCD, but Barriers Persist DBS is safe and effective for treatment-resistant obsessive–compulsive disorder that can be expected to produce significant clinical benefit in about 2 out of 3 cases, but insurance rarely pays.
  Medscape Medical News, September 27, 2022
• Biogen to Pay $900M to Settle Physician Kickback Allegations Former employee/whistleblower to receive $250 million as part of settlement involving three drugs used to treat muscular sclerosis.
  Medscape Medical News, September 27, 2022
• Despite Benefits, Extended-Interval Pembro Uptake Remains Low New findings may ease lingering doubts about the therapeutic equivalence and safety of extended-interval vs standard dosing of pembrolizumab.
  Medscape Medical News, September 27, 2022
• Heart Failure Drug a New Treatment Option for Alcoholism? Spironolactone, a potassium-sparing diuretic typically used to treat heart failure and hypertension, has shown promise for alcohol use disorder, a common condition with few treatment options.
  Medscape Medical News, September 27, 2022
• Canadian Safer Opioid Supply Program Improves Outcomes A harm-reduction initiative reduced emergency department visits, hospitalizations, and healthcare costs among participants with opioid use disorder.
  Medscape Medical News, September 27, 2022
• Post-Transplant Diabetes Can Be Predicted in Kidney Recipients Combined family history and early postoperative plasma glucose, but not glycated albumin, predicted post-transplant diabetes mellitus in kidney recipients in a new study.
  First Look, September 27, 2022
• Allergies Cluster and Have Predictable Trajectories Allergic trajectories occur in clusters, arise from multiple factors, and are established by adolescence, researchers report.
  Medscape Medical News, September 27, 2022
• The COVID-19 Booster's Public Relations Problem With a new COVID booster rolling out, a leading expert explains how public health leaders have struggled to set expectations for the vaccine and convey clearly who benefits from each additional shot.
  ProPublica, September 27, 2022
• Preventing Doxorubicin-Induced Hand-Foot Syndrome Dexamethasone plus wrist and ankle cooling may prevent hand-foot syndrome from doxorubicin in patients with ovarian cancer. The study was published as a preprint and has not yet been peer reviewed.
  First Look, September 27, 2022
• EASD 2022 Does COVID-19 Cause Type 1 Diabetes in Kids? Time Will Tell Norwegian study finds association of SARS-CoV-2 with type 1 diabetes if diagnosed over 30 days after infection, while Scottish study finds no such link. More data are needed.
  Medscape Medical News, September 27, 2022
• New Update Focuses on Acute Kidney Injury Management in Cirrhosis Prevent volume loss, manage risk factors, hold beta blockers, and stop NSAIDs are among the key recommendations in a new update to prevent acute kidney injury in patients with cirrhosis.
  Medscape Medical News, September 27, 2022
• Psoriasis Drug May Have Some Cardiometabolic Benefits Nonrandomized trial shows 5%-6% reduction in both visceral and subcutaneous fat, but no effect on aortic vascular inflammation.
  Medscape Medical News, September 27, 2022
• Unconventional Wisdom: MDD Tied to Childhood Trauma Is Treatable Previous research suggests patients with major depression and a history of childhood trauma do not respond as well to standard depression treatment, but the largest meta-analysis to date suggests the opposite.
  Medscape Medical News, September 27, 2022
• Renowned Oncologist Nicholas Vogelzang, MD, Dies at 72 Vogelzang left his mark as a medical oncologist and cancer investigator, helping shepherd a handful of cancer drugs through clinical trials.
  Medscape Medical News, September 27, 2022
• Not Just a Bad Dream: Nightmares May Predict Dementia Frequent bad dreams during middle and older age may accelerate cognitive decline and increase risk for dementia, especially in men, new research suggests.
  Medscape Medical News, September 26, 2022