Internal Medicine News

• EULAR 2023 HIIT Has Sustainable Effects in Inflammatory Arthritis Patients in a randomized trial improved their cardiorespiratory fitness, but the positive response did not coincide with changes in pain or fatigue.
  Medscape Medical News, June 09, 2023
• Concomitant Med Use May Explain Poor Antidepressant Response Patients with "treatment-resistant depression" may be taking additional medications with side effects that interfere with antidepressant efficacy.
  Medscape Medical News, June 09, 2023
• ESOC 2023 Immediate Statin After Acute Stroke Reduces Disability Intensive statin therapy immediately after mild ischemic stroke or high-risk TIA reduces the risk for a poor functional outcome vs delaying 72 hours, the INSPIRES trial shows.
  Medscape Medical News, June 09, 2023
• SLEEP 2023 Sleep Moderates Impulsivity and Risky Media Use in Kids Impulsive adolescents who don't get an adequate amount of sleep are more likely to report watching mature-rated media content.
  Medscape Medical News, June 09, 2023
• High Risk for Recurrence After Acute Lower GI Bleeding A large observational study has found a high rate of rebleeding after hospitalization for acute lower GI bleeding; the study identified several targetable risk factors.
  Medscape Medical News, June 09, 2023
• CMSC 2023 Shingles Infection Rates Higher in Patients With MS "The take-home finding is that herpes zoster incidence is high among people with MS overall."
  MDedge News, June 09, 2023
• VA Study Finds Lower Racial Disparity in Melanoma Diagnoses The results might be explained by "all patients in the VA dataset having insured access to health care, regardless of socioeconomic status," the authors wrote.
  MDedge News, June 09, 2023
• German Experts Suggest How to Avoid Future Drug Shortages In Germany, drug shortages and supply problems have reached critical levels and are affecting the provision of care.
  Medscape Medical News, June 09, 2023
• Is the WHO's 'Active Aging' the Only Healthy Alternative? Although WHO understands the term "active" broadly, active-aging programs tend to focus on physical activity.
  Medscape Medical News, June 09, 2023
• EULAR 2023 EULAR PsA Update Emphasizes Safety, Non-MSK Manifestations The update builds on 2019 recommendations and incorporates safety concerns about JAK inhibitors, advises on differential drug efficacy across disease manifestations, and eliminates systemic steroids.
  Medscape Medical News, June 09, 2023
• Antibiotic Prophylaxis May Lower SSIs in Skin Cancer Surgery Microdose delivery of clindamycin reduced the rate of postoperative surgical site infections by almost two thirds; flucloxacillin, however, showed no significant benefit over the control.
  Medscape Medical News, June 09, 2023
• WHO Advises Against Nonsugar Sweeteners for Weight Control Replacing free sugars with nonsugar sweeteners does not help with weight control in the long-term, according to the World Health Organization.
  Medscape Medical News, June 09, 2023
• Doctors in France Facing Rising Tide of Verbal Abuse Although physical abuse and vandalism are in decline, verbal abuse of doctors has increased.
  Medscape Medical News, June 09, 2023
• Novel Agent Promising for Major Depression: Phase 3 Data Results of a phase 3 trial show that the investigational drug zuranolone improved depressive symptoms for patients with major depressive disorder.
  Medscape Medical News, June 09, 2023
• CMSC 2023 'Strikingly Positive' Effect of Novel MS Agent Phase 2 data on the investigational drug frexalimab show favorable safety and significant reduction in new T1 brain lesions in relapsing MS.
  Medscape Medical News, June 09, 2023
• Tirzepatide's Benefits Go Beyond GLP-1 Agonist Effects Tirzepatide's agonist effect on GIP receptors of isolated pancreatic islet cells appears responsible for a good portion of the drug's effects beyond its GLP-1 receptor agonism.
  Medscape Medical News, June 09, 2023
• German Government Discusses Noninvasive Prenatal Testing Lawmakers propose an interdisciplinary panel of experts to review the legal, ethical, and health policy bases for the health insurance companies' authorization of this testing.
  Medscape Medical News, June 09, 2023
• CMSC 2023 Ozanimod for Relapsing MS Shows Long-Term Safety, Efficacy "Serious infections did not vary by age, and there were too few serious events to identify any age-related trends by specific TEAE," the authors reported.
  MDedge News, June 09, 2023
• Alert EU Approves Bimekizumab for PsA and AxSpA The drug is the first IL-17 inhibitor approved to treat both conditions.
  Medscape Medical News, June 08, 2023
• Is ChatGPT a Friend or Foe of Medical Publishing? The popular AI chatbot has prompted journal editors to write new policies to address a wave of manuscripts that use ChatGPT and other tools like it.
  Medscape Medical News, June 08, 2023