Latest - Pathology & Lab Medicine

• ESMO 2021 BrighTNess Follow-Up Data Shed Light on TNBC Therapy Patients with triple negative breast cancer had improved event-free survival when carboplatin (but not the PARP inhibitor veliparib) was added to standard neoadjuvant chemotherapy.
  Medscape Medical News, September 18, 2021
• Alert FDA Panel Backs Pfizer's COVID Booster for 65 and Older, High Risk Pfizer's application for a third dose of its mRNA COVID-19 vaccine was earlier rejected by the panel for those 16 and over.
  Medscape Medical News, September 17, 2021
• ESMO 2021 Nivo/Ipi Combo Now 'Standard of Care' in Mesothelioma Patients with malignant pleural mesothelioma have a marked and sustained overall survival benefit with nivolumab and ipilimumab vs chemotherapy, even if they discontinue treatment.
  Medscape Medical News, September 17, 2021
• WCLC 2021 Improved Survival in Patients With NSCLC and Brain Metastases About a third of the patients with NSCLC and brain metastases treated with atezolizumab in combination with chemotherapy had overall survival improved to 2 years.
  Medscape Medical News, September 17, 2021
• WCLC 2021 'Urgent' Need to Understand Immunotherapy De-escalation in NSCLC The strong and durable response to immunotherapy in some patients suggests treatment could be reduced or withdrawn, but questions surround which patients will be ideal candidates, an expert argues.
  Medscape Medical News, September 17, 2021
• FDA Analysis Chills the Rush to Approve Boosters An FDA report released this week has added doubt to the outcome of an advisory committee meeting on Friday to consider a third booster dose for the Pfizer COVID vaccines.
  Medscape Medical News, September 16, 2021
• WCLC 2021 Tackling Grief, Loss in Patients With Advanced Lung Cancer Managing distress in patients with a life-limiting condition is challenging, but physicians have a host of strategies at their fingertips to help provide relief, according to palliative care experts.
  Medscape Medical News, September 16, 2021
• New Single-Swab Test for COVID-19, Flu, and Respiratory Viruses   WebMD's Chief Medical Officer, John Whyte, MD, speaks with Brian Caveney, MD, President & Chief Medical Officer, Labcorp Diagnostics, about a new EUA test that can differentiate between COVID-19, the flu, and respiratory syncytial virus (RSV).
  WebMD, September 16, 2021
• Gut Microbiome Could Make Weight Loss Easier for Some Researchers reveal differences in gut bacteria between people who did and did not lose weight 6 months to 1 year after a lifestyle modification program.
  Medscape Medical News, September 16, 2021
• Alert FDA Approves First Oral Drug for NSCLC With EGFR Exon20 Insertion The FDA has granted an accelerated approval to mobocertinib for the treatment of locally advanced or metastatic nonsmall cell lung cancer with a specific type of EGFR mutation.
  FDA Approvals, September 16, 2021
• Patients Panic as Docs Cut Off Breast Cancer Drug Many women who have difficult-to-treat metastatic breast cancer and who have positively responded to atezolizumab suddenly had their prescription discontinued.
  Medscape Medical News, September 16, 2021
• COVID-19 Risk Among EMS Exposed to Aerosolizing Procedures EMS providers could potentially be exposed to airborne aerosol particles produced by patients with COVID-19. What strategies could help limit on-the-job exposure?
  Emerging Infectious Diseases, September 16, 2021
• New Moderna Vaccine Data 'Support' Booster Shot After 8 Months The company has released new data on the waning of vaccine effectiveness over time.
  Medscape Medical News, September 15, 2021
• Pet Store Puppies Linked to Campylobacter Infections Puppies can carry very drug-resistant Campylobacter. You might not want them licking your face.
  Medscape Medical News, September 15, 2021
• The 9/11 Firefighters and Cancer Incidence: 'We Owe Them'   Whether or not the 9/11 firefighters are at increased risk for cancer, we owe them close and careful attention to their health, says Dr F. Perry Wilson.
  Medscape, September 15, 2021
• COVID Vaccine Preprint Study Prompts Twitter Outrage The authors' conclusions about rates of myocarditis after COVID vaccine in boys 12 to 17 years of age are attacked for supposedly stoking anti-vaccine sentiment.
  Medscape Medical News, September 15, 2021
• Alert FDA Grants Zanubrutinib an Accelerated Approval in MZL The US Food and Drug Administration has granted an accelerated approval to zanubrutinib for the treatment of adult patients with relapsed or refractory marginal zone lymphoma.
  FDA Approvals, September 15, 2021
• The Role of Probiotics in Mental Health Researchers are uncovering the intricate ways our gut bacteria contribute to several mental health conditions, in the hopes of someday treating the mind through the stomach.
  Medscape Medical News, September 15, 2021
• New Tool Better Predicts Subsequent Cancers in Child Survivors An eHealth cancer predisposition screening tool greatly increases the odds of predicting subsequent malignancies in childhood cancer survivors.
  Medscape Medical News, September 15, 2021
• CRISPR-Based Approaches for Detection of SARS-CoV-2 Might CRISPR-based approaches be viable alternatives to conventional RT-PCR methods for the efficient and accurate detection of SARS-CoV-2?
  Laboratory Medicine, September 15, 2021