Gastroenterology News

• Biosimilars and Patients: Addressing Safety, Cost, Anxiety Physicians can respond to pushback from patients on switching to a biosimilar by offering resources and discussing options for both biosimilar and reference drugs.
  Medscape Medical News, March 30, 2023
• Semaglutide Doesn't Improve Fibrosis in NASH-Related Cirrhosis Secondary outcomes related to cardiometabolic risk showed improvement.
  Medscape Medical News, March 29, 2023
• Gene Variants Plus H pylori Increase Risk of Gastric Cancer Individuals with inherited pathogenic variants in genes associated with homologous recombination of DNA who also had H pylori infections had a 3-fold higher risk for gastric cancer vs infected noncarriers.
  Medscape Medical News, March 29, 2023
• One or Two High-Step Days May Reduce Mortality Risks Adults who took roughly 4 miles of steps 1 or 2 days a week showed longevity benefits similar to those of adults with more days of similar step counts.
  MDedge News, March 29, 2023
• High EHR Burden for Some GI Providers EHR use may be particularly burdensome for physicians who specialize in inflammatory bowel disease or hepatology, as well as for nonphysician GI care providers.
  Medscape Medical News, March 29, 2023
• Use Age, Not Weight, to Screen for Diabetes; Assess Over 35s 'If we make decisions about diabetes testing based on weight, we will miss some people from racial and ethnic minority groups who are developing prediabetes and diabetes at lower weights,' says researcher.
  Medscape Medical News, March 28, 2023
• Plant-Based Diets Not Always Healthy; Quality Is Key 'Not all plant-based diets are created equally...For health benefits the plant-based sources need to be wholegrains, fruits, and vegetables, etc...rather than processed,' says researcher.
  Medscape Medical News, March 28, 2023
• No Added Benefit of Time-Restricted Eating in NAFLD Adding time-restricted eating to calorie restriction does not provide added benefits in adults with obesity and nonalcoholic fatty liver disease.
  Medscape Medical News, March 27, 2023
• GSK Loses Bid to Keep Experts Out of Upcoming Zantac Trial A California judge on Thursday denied GSK's bid to keep expert testimony linking its discontinued heartburn drug Zantac to cancer out of an upcoming trial, a setback for the British drugmaker.
  Reuters Health Information, March 24, 2023
• Alert FDA Approves New Formulation of Hyrimoz Adalimumab Biosimilar The agency approved a higher concentration formulation of Hyrimoz for its previous indications, including rheumatoid arthritis and psoriasis.
  Medscape Medical News, March 27, 2023
• Could a Baby's Gut Health Be an Early Predictor of Future T1D? The makeup of gut bacteria in those as young as aged 1 may predict future risk for developing type 1 diabetes, which could help identify those at high risk earlier.
  Medscape Medical News, March 27, 2023
• Ultraprocessed Foods and Cancer: Small Changes May Lower Risk A new analysis suggests that replacing just 10% of processed and ultraprocessed foods with minimally processed foods significantly lowered the risk for various cancers.
  Medscape Medical News, March 24, 2023
• Botulism Cases Linked to Intragastric Injections for Obesity Many cases were linked to two hospitals in Turkey, which is among the countries that perform the most cosmetic procedures, including those in which the botulism neurotoxin was used.
  Medscape Medical News, March 24, 2023
• Transplant Rethink Urged After Brain Tumor Donors Found Safe The risk for cancer transmission from organ donors with primary brain tumors is lower than previously thought, and organ usage from such donors could be expanded to tackle shortages, say UK researchers.
  Medscape Medical News, March 24, 2023
• Drug Developer 89Bio Soars as NASH Drug Succeeds in Midstage Study Drug developer 89Bio said on Wednesday its experimental treatment for liver disease NASH met the main goals of a small mid-stage study.
  Reuters Health Information, March 22, 2023
• Possible C. difficile–Colon Cancer Connection: Study Previous research has found that there is a higher amount of C diff in cancerous lesions than in healthy body tissue.
  WebMD Health News, March 22, 2023
• Consider Life Expectancy in Surveillance Colonoscopy Advice The likelihood of finding a concerning polyp on surveillance colonoscopy is low in older adults, yet most are advised to repeat the procedure even when they have limited life expectancy.
  Medscape Medical News, March 21, 2023
• Tissue-Sparing Resection, Ablation Option for NET Liver Mets Parenchymal-sparing liver resection with microwave ablation should be considered for NETs with many liver metastases. The study was published as a preprint and has not yet been peer reviewed.
  First Look, March 21, 2023
• AI-Assisted Colonoscopy Doesn't Always Improve Adenoma Detection Future studies could explore the various factors that may contribute to differences found in community-based versus academic settings.
  Medscape Medical News, March 20, 2023
• Has Germany's Plan for Reducing Sugar in Soft Drinks Failed? A strategy depending on voluntary changes by industry has been associated with a 2% reduction in sugar, which is far short of the target of a 15% reduction.
  Medscape Medical News, March 17, 2023