What is the effect on fertility of pediatric colorectal tumor treatments?

Updated: Jun 06, 2020
  • Author: Jaime Shalkow, MD, FACS; Chief Editor: Cameron K Tebbi, MD  more...
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Adhesions following pelvic surgery contribute to infertility risk in women. Pelvic radiation for rectal cancer is likely to cause premature ovarian failure. Options to prevent this complication include pre-radiation laparoscopic ovarian transposition or cryopreservation.

Chemotherapy can also impair reproductive health. Fluorouracil is not likely to cause infertility, but oxaliplatin has been associated with moderate infertility risk in animal studies.

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