What is juvenile polyposis syndrome (JPS)?

Updated: Jun 06, 2020
  • Author: Jaime Shalkow, MD, FACS; Chief Editor: Cameron K Tebbi, MD  more...
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Juvenile polyposis syndrome (JPS) is a genetic disorder associated with an increased risk of colorectal cancer. It is diagnosed in patients with more than 5 polyps at the colon/rectum, multiple polyps throughout the upper and lower GI tract, or any number of lesions with a family history of juvenile polyposis.

Surgery may be offered when the patient has too many polyps to treat endoscopically, or for patients with GI bleeding, anemia, diarrhea, or protein-losing enteropathy. [8]

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