What is the clinical presentation of Pseudomonas bacteremia and sepsis?

Updated: Dec 17, 2018
  • Author: Selina SP Chen, MD, MPH; Chief Editor: Russell W Steele, MD  more...
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Bacteremia and sepsis

  • Clinical presentation is often identical to other gram-negative organisms.

  • Fever is usually present, except in very young or premature infants. Fever is often accompanied by tachycardia and tachypnea.

  • Patients appear toxic and may present with apprehension, disorientation, or obtundation.

  • Signs of shock, including hypotension, azotemia, or acute renal failure, may be observed.

  • Respiratory failure occurs in the presence of bacteremic pseudomonal pneumonia or in conjunction with airway restrictive disease syndrome.

  • Jaundice appears to occur more often than in other forms of gram-negative sepsis, but disseminated intravascular coagulation (DIC) is relatively uncommon.

  • Skin lesions may be an important distinguishing feature of pseudomonal bacteremia, especially typical EG lesions.

  • A diffuse maculopapular eruption, primarily on the trunk, has also been reported in early stages of pseudomonal sepsis. Metastatic abscesses of the extremities and fingertips occasionally manifest later in the course of the disease.

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