What is the global prevalence of Pseudomonas infections?

Updated: Dec 17, 2018
  • Author: Selina SP Chen, MD, MPH; Chief Editor: Russell W Steele, MD  more...
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Numerous B cepacia epidemics associated with CF have been reported. A particular highly transmissible strain, which spread epidemically within and between CF centers in Western Europe and the United States, carries the cblA gene. This cblA strain has spread across Canada and now has been isolated in 50% of CF centers in the United Kingdom. Another strain of B cepacia has been found in CF centers in 4 regions of France. The propensity for transmission evidently varies among strains; most strains are not involved in epidemics but appear to be acquired independently without evidence of epidemic transmission.

A study reviewed German NICU surveillance data on more than 44,000 infants below 1500 g birth weight with the aim to quantify the pathogen-specific risk of a blood stream infection in preterm infants after an index case of the same pathogen in the NICU department. The relative risk was markedly elevated for Serratia and Pseudomonas aeruginosa.  With only 38 cases of Pseudomonas aeruginosa out of the 2004 culture-positive infections, the relative risk was still high at 64.5. [5]

Glanders caused by B mallei has not occurred in the United States since the 1940s, although it remains common in domestic animals in Africa, Asia, the Middle East, Central America, and South America.

Melioidosis caused by B pseudomallei is endemic in Southeast Asia. The highest concentrations of cases occur in Vietnam, Cambodia, Laos, Thailand, Malaysia, Myanmar (formerly Burma), and northern Australia. Melioidosis also occurs in the South Pacific, Africa, India, and the Middle East. The B pseudomallei organism is so prevalent that it is often found as a contaminant.

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