What is the prevalence of B cepacia infection in cystic fibrosis?

Updated: Dec 17, 2018
  • Author: Selina SP Chen, MD, MPH; Chief Editor: Russell W Steele, MD  more...
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B cepacia is associated with increased illness and death in patients with CF. In several small focal hospital outbreaks that involved patients who did not have CF, the typical cause was a contaminated common source (eg, IV solutions, disinfectant preparations). In the early 1980s, the organism emerged as a major threat, causing superinfection in as many as 40% of patients in some CF centers. Approximately 35% of patients infected with B cepacia develop accelerated pulmonary deterioration or fulminant necrotizing pneumonia with rapidly fatal bacteremia, a condition also referred to as cepacia syndrome.

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