How is severe neonatal varicella treated?

Updated: Nov 30, 2018
  • Author: Kirsten A Bechtel, MD; Chief Editor: Russell W Steele, MD  more...
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When maternal varicella has developed within 5 days before or 2 days after delivery, neonatal varicella is likely to be severe and disseminated. Prophylaxis or treatment is required with VZIG and acyclovir. Without these drugs, mortality rates may be as high as 30%. The primary causes of death are severe pneumonia and fulminant hepatitis.

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