How is varicella zoster immune globulin (VariZIG) administered in the prevention of pediatric chickenpox?

Updated: Nov 30, 2018
  • Author: Kirsten A Bechtel, MD; Chief Editor: Russell W Steele, MD  more...
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VariZIG is administered intramuscularly, never intravenously. The dose is 125 U/10 kg body weight. Administration as soon as possible after exposure is best, but it can prevent or attenuate varicella if administered within 10 days (ideally within 96 hours) of contact. The expected duration of protection is approximately 3 weeks.

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