Which factors affect the severity of neonatal varicella?

Updated: Nov 30, 2018
  • Author: Kirsten A Bechtel, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

Neonatal varicella can be a serious illness, depending on the timing of maternal varicella and delivery. After the initial viremia, the mother develops antibodies against the varicella virus. The severity of the disease in the newborn depends on whether transplacental passage includes only the virus or includes both the virus and the antibodies.


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