Which adjunctive medications are used in the treatment of Kawasaki disease?

Updated: Jul 29, 2018
  • Author: Tina K Sosa, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

Statins are another class of medications that have been used variably in the setting of KD, due to their cholesterol-lowering and immunomodulatory properties. Further research is necessary to determine the impact of statins in the early phase of KD as well as the potential to lower the risk for atherosclerosis in the long term.

The roles of other adjunctive therapies, including pentoxifylline and abciximab, have not yet been definitively determined. Pentoxifylline acts as an anti-inflammatory agent by inhibiting tumor necrosis factor-alpha and may reduce the incidence of aneurysms. Abciximab is a platelet glycoprotein IIb/IIIa receptor inhibitor and has been used in conjunction with standard therapies in patients with KD and giant aneurysms.


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