What is the role of respiratory viruses in the pathogenesis of Kawasaki disease?

Updated: Jul 29, 2018
  • Author: Tina K Sosa, MD; Chief Editor: Russell W Steele, MD  more...
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A study that reported on the role of respiratory viruses in the pathogenesis of KD found that more than 40% of children with KD also tested positive for respiratory viruses when they were admitted to the hospital. As a result, the authors note that a positive respiratory viral PCR or presence of respiratory symptoms at the time of presentation should not be used to exclude a diagnosis of KD. [58, 59]  Aside from infections, KD also has overlap with numerous drug hypersensitivity reactions and rheumatologic disorders, including juvenile idiopathic arthritis and systemic lupus erythematosus, which should be considered..

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