What causes Kawasaki disease?

Updated: Jul 29, 2018
  • Author: Tina K Sosa, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

The etiology of KD remains unknown. There has been a strong suspicion that the etiology of KD is infectious; however, no single infectious agent has been implicated. However, autoimmune reactions and genetic predisposition have been suggested as possible etiologic factors. By 2014, 6 genetic loci were linked to KD through genome-wide studies. However, the etiology of KD is complex, and these genetic factors still need to be fully applied to diagnosis and treatment. [15]


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