What is the prognosis of cholera?

Updated: Feb 03, 2021
  • Author: Sajeev Handa, MBBCh, BAO, LRCSI, LRCPI; Chief Editor: Russell W Steele, MD  more...
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Answer

Before the development of effective regimens for replacing fluids and electrolyte losses, the mortality in severe cholera was more than 50%. Mortality is higher in pregnant women and children. Mortality rates are lowest where intravenous therapy is available. Average case fatality rates for Europe and the Americas continue to hover around 1%. At the Treatment Center of the International Center for Diarrheal Disease Research, Bangladesh, less than 1% of patients with severe dehydration die.

In Africa, a marked decline in case fatality rates has occurred since 1970; however, Africa continues to have the highest reported case fatality rates (approximately 4% in 1999) compared with the rest of the world. Low case fatality rates have been achieved in South America, presumably because of the availability of adequate treatment facilities and trained personnel.


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