What is the infectious dose of Vibrio (V) cholerae required to cause cholera?

Updated: Feb 03, 2021
  • Author: Sajeev Handa, MBBCh, BAO, LRCSI, LRCPI; Chief Editor: Russell W Steele, MD  more...
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Answer

The infectious dose of V cholerae required to cause clinical disease varies by the mode of administration. If V cholerae is ingested with water, the infectious dose is 103 -106 organisms. When ingested with food, fewer organisms (102 -104) are required to produce disease.


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