What should be included in the differential diagnoses for supraclavicular lymph nodes lymphadenitis?

Updated: Feb 12, 2019
  • Author: Elizabeth Partridge, MD, MPH, MS; Chief Editor: Russell W Steele, MD  more...
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Answer

Supraclavicular lymph nodes

Supraclavicular lymph nodes receive lymphatic drainage from the chest and mediastinum.

Infections associated with supraclavicular lymph nodes are as follows:

  • Intrathoracic mycobacterial, fungal infections (not bacterial pneumonias or bronchial infections)

Malignancies associated with supraclavicular lymph nodes are as follows (Note: supraclavicular lymphadenitis is an ominous sign of malignancy):

  • Intrathoracic and intra-abdominal malignancies (Note: left-sided supraclavicular sentinel node or the Virchow node is highly suggestive of an occult abdominal neoplasm.)

  • Breast cancer

Other diseases associated with supraclavicular lymph nodes are as follows:

  • Sarcoidosis

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