Which infectious conditions are included in the differential diagnoses of histiocytosis?

Updated: Sep 16, 2020
  • Author: Cameron K Tebbi, MD; Chief Editor: Vikramjit S Kanwar, MBBS, MBA, MRCP(UK), FAAP  more...
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Answer

Other histiocytosis disorders, such as sinus hyperplasia and sinus histiocytosis with sinus histiocytosis with massive lymphadenopathy (SHML), or Rosai-Dorfman disease, must be differentiated from viral, bacterial, acid-fast bacterial, and parasitic infections. These infections may produce signs, symptoms, and hematologic findings similar to those of SHML. When tests for rheumatoid factor and lupus erythematosus yield positive results, these disorders may need to be considered.


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