How does hemophilia C (deficiency of factor XI) present during surgical procedures?

Updated: Dec 18, 2020
  • Author: Vineeta Gupta, MD, DNB, MAMS, FRCPCH, FUICC; Chief Editor: Hassan M Yaish, MD  more...
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Treatment of patients with factor XI deficiency is a challenge. Patients with severe deficiency are clearly and commonly at risk of bleeding from surgical procedures. Bleeding in these patients can start at the time of injury, or it can be delayed for several hours; it may persist until specific treatment is administered or it can stop on its own.

Bleeding is much more likely in relation to surgery in areas of high fibrinolytic activity and is less common in other procedures.

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