What is the role of biopsy in the diagnosis of pediatric breast disorders?

Updated: May 03, 2021
  • Author: Harsh Grewal, MD, FACS, FAAP; Chief Editor: Robert K Minkes, MD, PhD  more...
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In very young and preadolescent children, a biopsy should be considered with extreme caution because the developing breast bud may be irreparably harmed, even with a needle aspirate. Discrete masses should almost always be removed in boys and postpubertal girls unless the clinical and imaging features are characteristic for benign fibroadenoma, in which case observation with follow-up examination is an option. Excisional biopsies are usually performed via a circumareolar incision; if the mass is distant from the areola, an incision directly overlying the mass may be used.

As previously discussed, biopsies are sometimes performed in adolescent girls being examined for various conditions, such as fibroadenomas, trauma-related masses, and fibrocystic changes.

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