What is the role of Cowden disease in the development of pediatric breast disorders?

Updated: May 03, 2021
  • Author: Harsh Grewal, MD, FACS, FAAP; Chief Editor: Robert K Minkes, MD, PhD  more...
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Cowden disease is characterized by multiple benign keratoses located at the mucocutaneous sites on the face, hands, feet, and forearms; goiter; lipomas; and uterine leiomyomas. Infiltrating ductal carcinoma of the breast may develop in 30% of these women; one third of these cases are bilateral. [36]

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