What is the role of imaging studies in the workup of growth hormone receptor deficiency (GHRD)?

Updated: Jan 15, 2019
  • Author: Arlan L Rosenbloom, MD; Chief Editor: Robert P Hoffman, MD  more...
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Answer

A left hand and wrist radiograph can be used to assess osseous maturation as is done with any other growth disorder. 

A hip radiograph series may be indicated to assess for Legg-Perthes disease (aseptic necrosis of the capital femoral epiphysis).

Patients being treated with rhIGF-I may need radiographic studies of the upper airway to screen for the common adverse effect of lymphoid hyperplasia, which often requires tonsillectomy/adenoidectomy. 

Brain imaging studies may be required because of the adverse effect of intracranial hypertension.


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