Which medications and supplements may have negative interactions with attention deficit hyperactivity disorder (ADHD)-related medications?

Updated: Sep 09, 2021
  • Author: Maggie A Wilkes, MD; Chief Editor: Caroly Pataki, MD  more...
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Screen for the following medications or supplements that may have negative interactions with ADHD (ADD)-related medications:

  • Anticonvulsant agents

  • Antihypertensive agents

  • Caffeine-containing drugs

  • Pseudoephedrine

  • Ephedra

  • Monoamine oxidase inhibitors (MAOIs)

  • All medications known to be metabolized by means of the cytochrome P450 (CYP) 2D6 hepatic pathway (See the discussion about atomoxetine in the Medication section.)

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