Which conditions are included in the differential diagnoses of mold allergy?

Updated: Dec 02, 2020
  • Author: Shih-Wen Huang, MD; Chief Editor: Harumi Jyonouchi, MD  more...
  • Print

Other diseases that should be excluded include the following:

  • Cryptogenic fibrosing alveolitis

  • Pneumoconiosis

  • Tuberculosis

  • Metastatic cancer of the lung

Any infection, inflammation, or drug reaction leading to a fibrotic process of the lung also should be considered as differential diagnosis.

Worth re-emphasis is that mold-exposed patients can present with various immunoglobulin E (IgE)-mediated and non-IgE-mediated symptoms. Mycotoxins, irritation by spores, or metabolites may be culprits in non-IgE–mediated presentations; environmental assays have not been perfected. Symptoms attributable to the toxic effects of molds and not attributable to IgE or other immune mechanisms need further evaluation regarding their pathogenesis. However, immune, rather than toxic, responses seemed to be the major causes of symptoms in most studies.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!