Which physical findings are characteristic of mold-related allergic asthma?

Updated: Dec 02, 2020
  • Author: Shih-Wen Huang, MD; Chief Editor: Harumi Jyonouchi, MD  more...
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Signs include cough, wheezing, prolonged expiration, and tachypnea.

A deformed chest wall (eg, pigeon breast, barrel chest) is sometimes observed in children, especially in those with chronic allergic asthma.

Depending on the frequency of wheezing in the daytime and nighttime, asthma can be classified as mild intermittent, mild persistent, moderate persistent, or severe persistent according to the National Asthma Education and Prevention Program Expert Panel Report 2: Guidelines for the Diagnosis and Management of Asthma published by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH). [21]

In murine model of chronic fungal asthma, toll-like receptor 2 (TLR2) mediated signaling was shown to be a major contributing factor to maintain type 2 T-helper (Th2)-cytokine driven, anti-fungal innate response.

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