Which age groups have the highest prevalence of mold allergy?

Updated: Dec 02, 2020
  • Author: Shih-Wen Huang, MD; Chief Editor: Harumi Jyonouchi, MD  more...
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Mold allergy is prevalent in all age groups, and it may occur in young children secondary to indoor exposure to mold.

Allergic rhinitis and allergic asthma can occur in children and adults. ABPM and EAA are rare in children. ABPA has been reported in children of all ages, especially in those with CF.

In children with Alternaria -sensitive moderate-to-severe asthma, an increased type 2 helper cell (Th2) sensitivity to Alternaria stimulation was noted. [14] This was associated with a human leukocyte antigen (HLA)-DR restriction, and with increased frequency of HLA-DRB1*13 and HLA-DRB1*03. A decreased frequency of HLA-DQB1*03 was noted in Alternaria -sensitive moderate-to-severe asthma, suggesting HLA-DQB1*03 may be protective to the development.

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