Answer
See the list below:
-
Group I: Thirteen percent of all patients with rhabdomyosarcoma are in group I. This group is defined by localized disease with complete surgical resection and no evidence of regional nodal involvement.
-
Group II: Twenty percent of patients with rhabdomyosarcoma are in group II.
Group IIA patients have grossly resected disease with microscopic residual disease and no regional involvement.
Group IIB patients have had complete resection with no residual disease, but they also have regional disease with involved nodes.
Group IIC is a hybrid of groups IIA and IIB, containing patients with microscopic residual disease and regional nodal involvement.
-
Group III: Approximately 48% of patients with rhabdomyosarcoma are in group III. This group is marked by incomplete resection or biopsy only; therefore, it is characterized as gross residual disease.
-
Group IV: Approximately 18% of patients with rhabdomyosarcoma are in group IV. Individuals in group IV have distant metastasis at the time of diagnosis.
-
Embryonal rhabdomyosarcoma is evidenced by a variable cell population consisting of small, round tumor cells with hyperchromatic nuclei and of large, polygonal-shaped tumor cells with abundant eosinophilic cytoplasm, which often contains diagnostic cross striations (arrow). Image provided by Scott Kilpatrick, MD, Department of Pathology, University of North Carolina Hospitals.
-
Alveolar rhabdomyosarcoma is evidenced by uniform cell population consisting of cells with a high nuclear-to-cytoplasmic ratio. The cells are arranged in variably sized nests separated by fibrous tissue septa. In places, the cells appear loosely dispersed, mimicking a pulmonary alveolar pattern. Image provided by Scott Kilpatrick, MD, Department of Pathology, University of North Carolina Hospitals.
-
Axial CT scan of rhabdomyosarcoma in the left middle ear. Image provided by Suresh Muhkerji, MD, Department of Radiology, University of North Carolina Hospitals.
-
Axial CT scan of left orbital rhabdomyosarcoma. Image provided by Suresh Muhkerji, MD, Department of Radiology, University of North Carolina Hospitals.
-
Axial CT scan of right masticator space rhabdomyosarcoma. Image provided by Suresh Muhkerji, MD, Department of Radiology, University of North Carolina Hospitals.
-
MRI of right masticator space rhabdomyosarcoma. Image provided by Suresh Muhkerji, MD, Department of Radiology, University of North Carolina Hospitals.
