What is included in the workup of rhabdomyosarcoma?

Updated: Feb 01, 2019
  • Author: Amelia F Drake, MD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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The initial diagnostic workup must address 2 key issues. First, the nature and extent of the primary disease must be determined. To accomplish this, surgical biopsy is performed early in the diagnostic process. In addition, either CT or MRI is performed to provide accompanying information that is used in planning the approach for surgical resection as well as routes and doses for possible radiation therapy later in the treatment process.

Next, the clinician must evaluate the patient for locoregional or metastatic disease. This evaluation is accomplished by performing a battery of adjunctive studies, including bone marrow biopsy, chest CT, and technetium diphosphonate bone scanning. When the primary site is parameningeal, lumbar puncture is also performed for CSF cytology.

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