What are the histologic characteristics of botryoid rhabdomyosarcoma?

Updated: Feb 01, 2019
  • Author: Amelia F Drake, MD; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Botryoid type, a subset of embryonal rhabdomyosarcoma, accounts for 6% of all cases of rhabdomyosarcoma. This subtype characteristically arises under the mucosal surfaces of body orifices; therefore, it is most commonly observed in areas such as the vagina, bladder, and nares. It is distinguished by the formation of polypoid and grapelike tumor masses. On histologic study, botryoid rhabdomyosarcoma demonstrates malignant cells in an abundant myxoid stroma.

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