What causes increased heat production in cocaine toxicity?

Updated: Dec 31, 2020
  • Author: Lynn Barkley Burnett, MD, EdD, JD; Chief Editor: Sage W Wiener, MD  more...
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Cocaine affects the anterior hypothalamus, which increases the thermoset point. Agitation secondary to intoxication results in increased motor activity, which causes increased heat production.

Rule out occult infections in patients with fever.

Evaluate patients with abdominal or back pain for renal infarction.

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