Which lab tests are performed in the diagnosis evaluation of cocaine toxicity?

Updated: Dec 31, 2020
  • Author: Lynn Barkley Burnett, MD, EdD, JD; Chief Editor: Sage W Wiener, MD  more...
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If history is absent or if the patient has moderate to severe toxicity, appropriate laboratory tests may be ordered, including the following:

  • Complete blood count (CBC)
  • Electrolytes, blood urea nitrogen (BUN), creatinine, glucose (Chem-7)
  • Glucose
  • Pregnancy test
  • Calcium
  • Arterial blood gases (ABG) analysis
  • Creatine kinase (CK) level
  • Troponin (in patients complaining of chest pain)
  • Urinalysis (UA): Can aid in finding cocaine-induced rhabdomyolysis, the reported incidence of which is 5-30% in ED patients who use cocaine
  • Toxicology evaluations: Including for urine, blood, gastric contents, and unknown substances clinging to the patient’s body

See Workup for more detail.

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