Which medications in the drug class Antibiotic, Penicillin and Beta-lactamase Inhibitor are used in the treatment of Caustic Ingestions?

Updated: Dec 09, 2020
  • Author: Derrick Lung, MD, MPH, FACEP, FACMT; Chief Editor: David Vearrier, MD, MPH  more...
  • Print
Answer

Antibiotic, Penicillin and Beta-lactamase Inhibitor

These agents should be administered if evidence of perforation exists. A third-generation cephalosporin or ampicillin/sulbactam may be considered.

Ampicillin and sulbactam (Unasyn)

Drug combination of beta-lactamase inhibitor with ampicillin. Interferes with bacterial cell wall synthesis during active replication, causing bactericidal activity against susceptible organisms. Alternative to amoxicillin when unable to take medication orally.

Covers skin, enteric flora, and anaerobes. Not ideal for nosocomial pathogens.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!