What is the role of steroids in the treatment of caustic ingestions?

Updated: Dec 09, 2020
  • Author: Derrick Lung, MD, MPH, FACEP, FACMT; Chief Editor: David Vearrier, MD, MPH  more...
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Answer

Corticosteroids remains a controversial treatment to attempt to decrease morbidity from caustic and corrosive injuries. Early use was driven by decreased stricture formation in animal models, but this benefit was not demonstrated in subsequent patient cohorts. [17, 18]  A more recent study that focused on high risk injuries only found a benefit from a short 3-day course (in contrast to longer duration treatment in earlier studies) of methylpredisonolone in pediatric patients with grade 2B esophageal injuries. [19] At this time, recommendations on the use, dose, and duration of corticosteroids remains contentious even among exper.ts in the field.


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