What are the possible adverse effects of targeted temperature management (TTM)?

Updated: Jul 26, 2019
  • Author: Alex Koyfman, MD; Chief Editor: Karlheinz Peter, MD, PhD  more...
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Hypothermia is associated with a number of adverse effects and complications. The main adverse effects reported are shivering, cardiac arrhythmia, sepsis, coagulopathy, and electrolytes and metabolic disturbances. [76, 77]  Cold diuresis and hypovolemia may result. However, many large clinical trials and meta-analyses have reported these adverse effects to be infrequent. A trend toward increased incidence of sepsis has been noted.

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