What are relative contraindications for use of alteplase in thrombolytic therapy for acute ischemic stroke (AIS)?

Updated: Aug 04, 2021
  • Author: Wanda L Rivera-Bou, MD, FAAEM, FACEP; Chief Editor: Erik D Schraga, MD  more...
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Relative contraindications for alteplase therapy for AIS include the following:

  • Pregnancy
  • Rapidly improving stroke symptoms
  • Myocardial infarction (MI) in the previous 3 months
  • Glucose level lower than 50 mg/dL or higher than 400 mg/dL

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