Which patients with acute ischemic stroke (AIS) do not require thrombolytic therapy?

Updated: Aug 04, 2021
  • Author: Wanda L Rivera-Bou, MD, FAAEM, FACEP; Chief Editor: Erik D Schraga, MD  more...
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Patients with an NIH Stroke Scale score higher than 22 are considered to be at high risk for hemorrhagic conversion because of the probability of a large infarcted area. Patients with a score lower than 4 have only minor neurologic deficits, for which thrombolytic therapy is not indicated. On CT, high-risk patients often have early changes showing a large area of edema or mass effect.

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