How are fibrinolytic agents administered in thrombolytic therapy?

Updated: Aug 04, 2021
  • Author: Wanda L Rivera-Bou, MD, FAAEM, FACEP; Chief Editor: Erik D Schraga, MD  more...
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Fibrinolytic agents can be administered systematically or can be delivered directly into the area of the thrombus. Systemic delivery is used for treatment of AMI, acute ischemic stroke (AIS), and most cases of acute massive PE. Peripheral arterial thrombi and thrombi in the proximal deep veins of the leg are most often treated via a catheter-directed approach. [3]

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