What is the role of opioids in emergency department (ED) sedation?

Updated: Nov 06, 2018
  • Author: Arul M Lingappan, MD; Chief Editor: Erik D Schraga, MD  more...
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Opioids are agents that induce systemic analgesia, some anxiolysis, and mild sedation. They do not induce amnesia of any significance. Opioids are typically coadministered with benzodiazepines for added sedation, anxiolysis, and amnesia. They act by binding to specific opioid receptors in the CNS. They are the class of drugs most commonly used for pain management.

Opioids include morphine, fentanyl, and meperidine.

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