How is preoxygenation administered for rapid sequence intubation (RSI)?

Updated: Apr 07, 2020
  • Author: Keith A Lafferty, MD; Chief Editor: Guy W Soo Hoo, MD, MPH  more...
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Administer 100% oxygen via a nonrebreather mask for 3 minutes for nitrogen washout. This is done without positive pressure ventilation using a tight seal.

Though rarely possible in the emergent situation, the patient can take 8 vital capacity (as deep as possible) breaths of 100% oxygen. Studies have shown this can prevent apnea-induced desaturation for 3-5 minutes. [47]

Assist ventilation with bag-valve-mask (BVM) system only if needed to obtain oxygen saturation =90%.

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