Which topical antimicrobial agents are used in the treatment of acute conjunctivitis (pink eye)?

Updated: Mar 03, 2021
  • Author: Michael A Silverman, MD, FACEP; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Treatment with antimicrobials and symptomatic therapy is recommended for all patients initially presenting to the emergency department (ED) with simple conjunctivitis. Numerous topical antimicrobial agents may be used, including topical sulfacetamideerythromycingentamicinciprofloxacin, gatifloxacin, or ofloxacin. Avoid neomycin-containing solutions because 8-15% of patients have hypersensitivity reactions. Instill drops every 2 hours. An ointment can be used at night or every 4-6 hours throughout the day.

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