How does bilateral versus unilateral disease compare in the clinical evaluation for acute conjunctivitis (pink eye)?

Updated: Mar 03, 2021
  • Author: Michael A Silverman, MD, FACEP; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Bilateral disease is typically infectious or allergic. Unilateral disease suggests toxic, chemical, mechanical, or lacrimal origin. Intraocular pressure, pupil size, and light response are all normal in unilateral disease, and ciliary flush, corneal staining, and anterior chamber reaction is absent unless a significant amount of keratitis is associated (as seen in epidemic keratoconjunctivitis [EKC]).

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