Which nonspecific symptoms are associated with mild acute cell-mediated rejection in liver transplant patients?

Updated: Dec 31, 2017
  • Author: Lemi Luu, MD, RDMS, FACEP, FAAEM; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Acute cell-mediated rejection is not uncommon in the first 3 months following transplant and decreases in frequency with time. Symptoms of mild rejection are nonspecific and may include the following:

  • Low-grade fever
  • Fatigue
  • Malaise
  • Generalized weakness
  • Jaundice

Right-upper-quadrant pain also may be present. The rejection process may be subclinical, with laboratory abnormalities as the only sign of its presence.

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