Which medications in the drug class Fluoroquinolones are used in the treatment of Appendicitis?

Updated: Jul 23, 2018
  • Author: Sandy Craig, MD; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Answer

Fluoroquinolones

These agents can be used to relieve acute undifferentiated abdominal pain in patients presenting to the ED.

Ciprofloxacin (Cipro)

Ciprofloxacin is a fluoroquinolone that inhibits bacterial DNA synthesis and, consequently, growth, by inhibiting DNA gyrase and topoisomerase, which are required for replication, transcription, and translation of genetic material. Quinolones have broad activity against gram-positive and gram-negative aerobic organisms.

Levofloxacin (Levaquin)

Levofloxacin is used for infections caused by various gram-negative organisms, antipseudomonal infections due to multidrug resistant gram-negative organisms.

Moxifloxacin (Avelox)

Moxifloxacin is a fluoroquinolone that inhibits A subunits of DNA gyrase, inhibiting bacterial DNA replication and transcription.


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